Pub. Date : 2019
PMID : 31308744
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1. | linc01116 | fibronectin 1 | Mus musculus |
| 2 | In addition, the interaction among LINC01116, miR-136, and FN1 was identified. | linc01116 | fibronectin 1 | Mus musculus |
| 3 | LINC01116 could competitively bind to miR-136, which targets and negatively regulates FN1. | linc01116 | fibronectin 1 | Mus musculus |
| 4 | Conclusion: The fundamental findings in this study collectively demonstrate that LINC01116 silencing may inhibit the progression of OSCC via the miR-136-mediated FN1 inhibition, highlighting a promising therapeutic strategy for OSCC treatment. | linc01116 | fibronectin 1 | Mus musculus |