Pub. Date : 2019 Dec
PMID : 31302720
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: The alpha7 full orthosteric agonist PNU282987 and the Type II alpha7 nAChR PAM PNU120596 reduced nicotine CPP, while the silent agonist NS6740 and Type I PAM NS1738 had no effect. | 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | In addition, the Type II alpha7 nAChR PAM PNU120596 attenuated nicotine reward suggesting that endogenous acetylcholine/choline tone is sufficient to reduce nicotine CPP. | 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |