Pub. Date : 2019 Jul 11
PMID : 31301417
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition, treatment with cinobufagin could dramatically increase the expression of ROS and then activate the phosphorylation of MAPK family proteins, including ERK 1/2, JNK and p38. | cinobufagin | mitogen-activated protein kinase 1 | Homo sapiens |
2 | What"s more, the reaction of apoptosis and autophagy induced by cinobufagin treatment could be reversed by p38 inhibitor SB203580 and JNK inhibitor SP600125 as well as ROS exclusive inhibitor antioxidant N-acetyl cysteine (NAC). | cinobufagin | mitogen-activated protein kinase 1 | Homo sapiens |