Title : Sulforaphane protects against ethanol-induced apoptosis in neural crest cells through restoring epithelial-mesenchymal transition by epigenetically modulating the expression of Snail1.

Pub. Date : 2019 Oct 1

PMID : 31295528






2 Functional Relationships(s)
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Protein Name
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1 Treatment with SFN also dramatically diminished ethanol-induced changes in the expression of E-cadherin and vimentin, and restored EMT in ethanol-exposed NCCs. sulforaphane cadherin 1 Homo sapiens
2 SFN treatment diminished the ethanol-induced reduction of H3K4me3 at the promoter regions of the Snail1 gene, restored the expression of Snail1 and down-regulated Snail1 target gene E-cadherin. sulforaphane cadherin 1 Homo sapiens