Title : Characterization of the in vitro CYP450 mediated metabolism of the polymorphic CYP2D6 probe drug codeine in horses.

Pub. Date : 2019 Oct

PMID : 31295464






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP3A95, which shares 79% sequence homology with human CYP3A4 and CYP2D50 catalyzed the conversion of codeine to norcodeine (Km of 104.1 and 526.9 muM, Vmax of 2.8 and 2.6 pmol/min/pmol P450). norcodeine cytochrome P450 family 3 subfamily A member 4 Homo sapiens