Title : Transforming Growth Factor β Receptor Type I Inhibitor, Galunisertib, Has No Beneficial Effects on Aneurysmal Pathological Changes in Marfan Mice.

Pub. Date : 2019 Jul 9

PMID : 31284709






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mice treated with galunisertib or losartan barely exhibited phosphorylated Smad2, suggesting that both drugs effectively blocked overactivated canonical TGFbeta signaling in Fbn1C1039G/+ mice. Losartan SMAD family member 2 Mus musculus