Pub. Date : 2019
PMID : 31259152
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88. | ursolic acid | myeloid differentiation primary response gene 88 | Mus musculus |
| 2 | Meanwhile, the downregulation of MyD88 through the overexpression of miR-149-5p or UA treatment inhibited the activation of the Akt signaling pathway in 231/PTX cells. | ursolic acid | myeloid differentiation primary response gene 88 | Mus musculus |
| 3 | Thus, our data indicate that UA can reverse PTX resistance by targeting the miRNA-149-5p/MyD88 axis in breast cancer cells. | ursolic acid | myeloid differentiation primary response gene 88 | Mus musculus |