Pub. Date : 2019 Aug
PMID : 31257541
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sulforaphane has a therapeutic effect in an atopic dermatitis murine model and activates the Nrf2/HO-1 axis. | sulforaphane | heme oxygenase 1 | Mus musculus |
| 2 | Western blot assays revealed that the expression levels of nuclear factor-E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), which exhibit oxidation resistance, were increased by sulforaphane treatment in DNCB-induced AD mice. | sulforaphane | heme oxygenase 1 | Mus musculus |
| 3 | Western blot assays revealed that the expression levels of nuclear factor-E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), which exhibit oxidation resistance, were increased by sulforaphane treatment in DNCB-induced AD mice. | sulforaphane | heme oxygenase 1 | Mus musculus |
| 4 | The present study suggested that sulforaphane exerted a therapeutic effect in the AD mouse model through the activation of the Nrf2/HO-1 axis as well as the suppression of Janus kinase 1/STAT3 signaling pathway. | sulforaphane | heme oxygenase 1 | Mus musculus |