Title : Biphasic Effect of Sildenafil on Energy Sensing is Mediated by Phosphodiesterases 2 and 3 in Adipocytes and Hepatocytes.

Pub. Date : 2019 Jun 19

PMID : 31248114






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, further increases in cGMP from higher sildenafil concentrations activate PDE2 and consequently decrease cAMP, which demonstrates crosstalk between cAMP and cGMP via PDE2, PDE3, and PDE5. Cyclic GMP phosphodiesterase 5A Homo sapiens
2 However, further increases in cGMP from higher sildenafil concentrations activate PDE2 and consequently decrease cAMP, which demonstrates crosstalk between cAMP and cGMP via PDE2, PDE3, and PDE5. Cyclic GMP phosphodiesterase 5A Homo sapiens