Title : Interaction of tissue-type plasminogen activator and plasminogen activator inhibitor 1 on the surface of endothelial cells.

Pub. Date : 1988 Feb 5

PMID : 3123483






2 Functional Relationships(s)
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1 Moreover, 125I-labeled t-PA immobilized on Sepharose added directly to endothelial cells formed a complex with PAI-1 in a dose-dependent manner. Sepharose plasminogen activator, tissue type Homo sapiens
2 On the other hand, no detectable complex was formed with PAI-1 when Sepharose-immobilized 125I-labeled t-PA was added to endothelial cells under conditions in which the added t-PA could not contact the cells directly but other proteins could pass freely by the use of a Transwell. Sepharose plasminogen activator, tissue type Homo sapiens