Title : Interactions between iron and α-synuclein pathology in Parkinson's disease.

Pub. Date : 2019 Sep

PMID : 31233777






9 Functional Relationships(s)
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Protein Name
Organism
1 The direct structural links between iron and alpha-synuclein suggest that structural reorganization provokes alpha-synuclein conformational change. Iron synuclein alpha Homo sapiens
2 The direct structural links between iron and alpha-synuclein suggest that structural reorganization provokes alpha-synuclein conformational change. Iron synuclein alpha Homo sapiens
3 Iron post-transcriptionally regulates alpha-synuclein synthesis in the presence of iron-responsive element. Iron synuclein alpha Homo sapiens
4 Iron post-transcriptionally regulates alpha-synuclein synthesis in the presence of iron-responsive element. Iron synuclein alpha Homo sapiens
5 Increased oxidative/nitrative stress induced by iron is believed to be involved in the post-translational modulation of alpha-synuclein. Iron synuclein alpha Homo sapiens
6 Iron modulates proteolytic pathways and therefore participates in the regulation of alpha-synuclein levels. Iron synuclein alpha Homo sapiens
7 Finally, alpha-synuclein might regulate iron metabolism through its ferrireductase activity. Iron synuclein alpha Homo sapiens
8 A prominent role of alpha-synuclein in iron homeostasis is involved in the uptake of transferrin-Fe. Iron synuclein alpha Homo sapiens
9 A prominent role of alpha-synuclein in iron homeostasis is involved in the uptake of transferrin-Fe. Iron synuclein alpha Homo sapiens