Title : Role of Proinflammatory Cytokines in Feedback Modulation of Circadian Clock Gene Rhythms by Saturated Fatty Acids.

Pub. Date : 2019 Jun 20

PMID : 31222133






2 Functional Relationships(s)
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1 Because the cytokines TNFalpha and IL-6 are key signals in HFD- and SFA-induced proinflammatory responses that ultimately lead to systemic insulin resistance, the present study examined the roles of these cytokines in the feedback modulation of peripheral circadian clocks by the proinflammatory SFA, palmitate. Fatty Acids interleukin 6 Homo sapiens
2 These studies suggest that TNFalpha, IL-6 and other proinflammatory cytokines may mediate the feedback modulation of peripheral circadian clocks by SFA-induced inflammatory signaling. Fatty Acids interleukin 6 Homo sapiens