Title : Optical Control of the GTP Affinity of K-Ras(G12C) by a Photoswitchable Inhibitor.

Pub. Date : 2019 Dec 2

PMID : 31219673






2 Functional Relationships(s)
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1 Optical Control of GTP Affinity of K-Ras(G12C) by Photoswitchable Inhibitor. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens
2 Nucleotide exchange assay demonstrated the different efficacy to control GTP affinity by photoswitching of one potent compound PS-C2, which would be useful tool to probe the conformation of mutational K-Ras. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens