Title : Novel Pyrazoloquinolin-2-ones: Design, synthesis, docking studies, and biological evaluation as antiproliferative EGFR-TK inhibitors.

Pub. Date : 2019 Sep

PMID : 31212178






1 Functional Relationships(s)
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1 Moreover, the docking study indicated that both the pyrazole moiety and the quinolin-2-one ring showed good fitting into EGFR (PDB code: 1M17). pyrazole epidermal growth factor receptor Homo sapiens