Pub. Date : 2019 Dec 13
PMID : 31206933
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TRAIL-inspired multivalent dextran conjugates efficiently induce apoptosis upon DR5 receptor clustering. | Dextrans | TNF receptor superfamily member 10b | Homo sapiens |
| 2 | Enzyme-catalyzed ligation of a hydrophilic dextran conjugate bearing multiple DR5-targeting sites to a human Fc did not affect potency (EC50 = 2 - 7 nM), providing an option for improved in vivo half-life and prospective conjugation to an antibody of interest in view of bispecific tumor targeting. | Dextrans | TNF receptor superfamily member 10b | Homo sapiens |