Title : EGFR L718Q mutation occurs without T790M mutation in a lung adenocarcinoma patient with acquired resistance to osimertinib.

Pub. Date : 2019 May

PMID : 31205925






3 Functional Relationships(s)
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1 EGFR L718Q mutation occurs without T790M mutation in a lung adenocarcinoma patient with acquired resistance to osimertinib. osimertinib epidermal growth factor receptor Homo sapiens
2 Here we reported a case of lung adenocarcinoma patient who progressed on osimertinib with EGFR L718Q mutation in the absence of T790M mutation. osimertinib epidermal growth factor receptor Homo sapiens
3 This is the first clinical report of the use of the effective EGFR-TKI treatment after L718Q-induced osimertinib resistance. osimertinib epidermal growth factor receptor Homo sapiens