Pub. Date : 2019 Aug 25
PMID : 31176714
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aryl hydrocarbon receptor (AhR) is a highly conserved ligand-activated transcription factor with high affinity to aromatic planar compounds, such as beta-naphthoflavone (BNF), benzo[a]pyrene (BaP) or dioxin (TCDD). | beta-Naphthoflavone | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Aryl hydrocarbon receptor (AhR) is a highly conserved ligand-activated transcription factor with high affinity to aromatic planar compounds, such as beta-naphthoflavone (BNF), benzo[a]pyrene (BaP) or dioxin (TCDD). | beta-Naphthoflavone | aryl hydrocarbon receptor | Homo sapiens |
| 3 | Aryl hydrocarbon receptor (AhR) is a highly conserved ligand-activated transcription factor with high affinity to aromatic planar compounds, such as beta-naphthoflavone (BNF), benzo[a]pyrene (BaP) or dioxin (TCDD). | beta-Naphthoflavone | aryl hydrocarbon receptor | Homo sapiens |
| 4 | Aryl hydrocarbon receptor (AhR) is a highly conserved ligand-activated transcription factor with high affinity to aromatic planar compounds, such as beta-naphthoflavone (BNF), benzo[a]pyrene (BaP) or dioxin (TCDD). | beta-Naphthoflavone | aryl hydrocarbon receptor | Homo sapiens |
| 5 | To prove that such induction is really AhR-dependent, in the present study we knocked down the expression of AhR by stable transfection of a laryngeal squamous cell carcinoma cell line (UT-SCC-34) with shRNA, resulting in 92% reduction of BNF-induced expression of SERPINB2. | beta-Naphthoflavone | aryl hydrocarbon receptor | Homo sapiens |