Pub. Date : 2019
PMID : 31157167
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways. | triptolide | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Moreover, we found that triptolide induced ROS production and JNK activation and inhibited the activity of Akt and mTOR. | triptolide | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Collectively, these data indicated that triptolide induced G2/M phase arrest, apoptosis, and autophagy via activating the ROS/JNK and blocking the Akt/mTOR signaling pathways in glioma cells. | triptolide | mechanistic target of rapamycin kinase | Homo sapiens |