Pub. Date : 2019
PMID : 31155561
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Analogues possessing aromatic bicyclic systems at the C5 position of the central pyrazine ring exhibited superior AR inhibiting activity relative to the parent botryllazine A. | Pyrazines | aldo-keto reductase family 1 member B | Homo sapiens |
| 2 | Conversely, a benzoyl group-containing phenolic hydroxyl groups-at either position C2 or C3 of the pyrazine ring was essential for attainment of high inhibitory activity approaching that of sorbinil (a highly effective AR inhibitor). | Pyrazines | aldo-keto reductase family 1 member B | Homo sapiens |