Title : Development of potent aldose reductase inhibitors having a hydantoin structure.

Pub. Date : 1987 Sep 1

PMID : 3115267






2 Functional Relationships(s)
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1 Development of potent aldose reductase inhibitors having a hydantoin structure. Hydantoins aldo-keto reductase family 1 member B1 Rattus norvegicus
2 Seventeen hydantoin derivatives were tested as inhibitors of aldose reductase, an enzyme believed to participate in the initiation of diabetic complications. Hydantoins aldo-keto reductase family 1 member B1 Rattus norvegicus