Pub. Date : 2019 Sep 15
PMID : 31132711
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previously we have found that Aristaless-like Homeobox 4 (ALX4) was differentially expressed in MC-LR-induced malignant transformed L02 cells. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 2 | Previously we have found that Aristaless-like Homeobox 4 (ALX4) was differentially expressed in MC-LR-induced malignant transformed L02 cells. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 3 | However, the expression regulation, role and molecular mechanism of ALX4 during the process of liver cancer induced by MC-LR are still unclear. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 4 | The anti-tumor effects of ALX4 on MC-LR induced liver cancer were identified in vitro and in vivo. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 5 | ALX4 expression was progressively down-regulated in MC-LR-induced malignantly transformed L02 cells and the MC-LR exposed rat models. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 6 | ALX4 expression was progressively down-regulated in MC-LR-induced malignantly transformed L02 cells and the MC-LR exposed rat models. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |
| 7 | Our results suggested that ALX4 was inactivated by DNA methylation and played a tumor suppressor function through the P53 pathway in MC-LR induced liver cancer. | cyanoginosin LR | ALX homeobox 4 | Homo sapiens |