Pub. Date : 2019
PMID : 31130850
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Results: In this study, intraperitoneal injection of 1 mg/kg LPS induced mast cell activation in hypothalamus and cognitive dysfunction in rats, and that this process can be repressed by the mast cell stabilizer cromolyn (200 mug). | Cromolyn Sodium | toll-like receptor 4 | Mus musculus |
2 | We also found that LPS selectively provokes upregulation of H1R, H4R, PAR2, and TLR4, but downregulation of H2R and H3R, in ipsilateral hypothalamus microglia; these effects were partially inhibited by cromolyn. | Cromolyn Sodium | toll-like receptor 4 | Mus musculus |