Title : PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway.

Pub. Date : 2019 Aug 15

PMID : 31095939






4 Functional Relationships(s)
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1 In this study, we aimed to investigate whether PAQR3 regulates phosphorylation of FoxO1 via NF-kappaB pathway in palmitic acid (PA)-induced insulin-resistant HepG2 cells, thereby causing glucose and lipid metabolism disorders. Palmitic Acid insulin Homo sapiens
2 In this study, we aimed to investigate whether PAQR3 regulates phosphorylation of FoxO1 via NF-kappaB pathway in palmitic acid (PA)-induced insulin-resistant HepG2 cells, thereby causing glucose and lipid metabolism disorders. Palmitic Acid insulin Homo sapiens
3 Taken together, in PA-induced insulin-resistant HepG2 cells, PAQR3 might regulate the phosphorylation of FoxO1 and the expressions of GCK and LDLR through NF-kappaB pathway, thereby regulating the glucose and lipid metabolism disorders induced by insulin resistance. Palmitic Acid insulin Homo sapiens
4 Taken together, in PA-induced insulin-resistant HepG2 cells, PAQR3 might regulate the phosphorylation of FoxO1 and the expressions of GCK and LDLR through NF-kappaB pathway, thereby regulating the glucose and lipid metabolism disorders induced by insulin resistance. Palmitic Acid insulin Homo sapiens