Title : CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.

Pub. Date : 2019 May 16

PMID : 31095524






1 Functional Relationships(s)
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1 Inhibition of CBX5/G9a pathway in fibroblasts elevates PGC1alpha, attenuates TGFbeta- and matrix stiffness-promoted H3K9 methylation, and reduces collagen accumulation in the lungs following bleomycin injury. Bleomycin chromobox 5 Homo sapiens