Title : Impaired L-arginine metabolism marks endothelial dysfunction in CD73-deficient mice.

Pub. Date : 2019 Aug

PMID : 31093850






4 Functional Relationships(s)
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1 Impaired L-arginine metabolism marks endothelial dysfunction in CD73-deficient mice. Arginine 5' nucleotidase, ecto Mus musculus
2 All CD73-/- mice age groups were characterized by reduced L-Arginine concentration and eNOS level. Arginine 5' nucleotidase, ecto Mus musculus
3 The L-Arginine/ADMA ratio in the CD73-/- decreased in age-dependent manner in comparison to WT. Arginine 5' nucleotidase, ecto Mus musculus
4 The CD73 deletion leads to the development of age-dependent endothelial dysfunction in mice, associated with impaired L-arginine metabolism. Arginine 5' nucleotidase, ecto Mus musculus