Protein Name 5' nucleotidase, ecto
Organism Mus musculus
Gene ID 23959
Gene Symbol


UniProt Q61503 (5NTD_MOUSE), Q0VEE0 (Q0VEE0_MOUSE)
Relationships Total Number of functionally related compound(s) : 203
Total Number of Articles : 378

5' nucleotidase, ecto

Gene Summary

This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow. [provided by RefSeq, Sep 2016]

  • 5'-nucleotidase
  • 5'-deoxynucleotidase
  • IMP-specific 5'-nucleotidase
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