| Protein Name | 5' nucleotidase, ecto |
|---|---|
| Organism | Mus musculus |
| Gene ID | 23959 |
| Gene Symbol | Nt5e |
| UniProt | Q61503 (5NTD_MOUSE), Q0VEE0 (Q0VEE0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
203
Total Number of Articles : 378 |
Description |
5' nucleotidase, ecto |
| Gene Summary |
This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow. [provided by RefSeq, Sep 2016] |
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