Title : Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism.

Pub. Date : 2019 Apr 30

PMID : 31091555






2 Functional Relationships(s)
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1 Both metformin and CO can differentially induce several protein factors, including fibroblast growth factor 21 (FGF21) and sestrin2 (SESN2), which maintain metabolic homeostasis; nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of the antioxidant response; and REDD1, which exhibits an anticancer effect. Metformin NFE2 like bZIP transcription factor 2 Homo sapiens
2 Both metformin and CO can differentially induce several protein factors, including fibroblast growth factor 21 (FGF21) and sestrin2 (SESN2), which maintain metabolic homeostasis; nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of the antioxidant response; and REDD1, which exhibits an anticancer effect. Metformin NFE2 like bZIP transcription factor 2 Homo sapiens