Pub. Date : 2019 Jun 7
PMID : 31086893
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, a combination of absorption and electron paramagnetic resonance spectroscopy and kinetic assays have been used to study the interaction of nitrite with the metal bound Abeta complexes. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 2 | The data indicate that heme(III)-Cu(i)-Abeta, heme(II)-Cu(i)-Abeta, heme(II)-Abeta and Cu(i)-Abeta can reduce nitrite to nitric oxide (NO), an important biological messenger also related to AD, and thus behave as nitrite reductases. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 3 | The data indicate that heme(III)-Cu(i)-Abeta, heme(II)-Cu(i)-Abeta, heme(II)-Abeta and Cu(i)-Abeta can reduce nitrite to nitric oxide (NO), an important biological messenger also related to AD, and thus behave as nitrite reductases. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 4 | The data indicate that heme(III)-Cu(i)-Abeta, heme(II)-Cu(i)-Abeta, heme(II)-Abeta and Cu(i)-Abeta can reduce nitrite to nitric oxide (NO), an important biological messenger also related to AD, and thus behave as nitrite reductases. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 5 | The data indicate that heme(III)-Cu(i)-Abeta, heme(II)-Cu(i)-Abeta, heme(II)-Abeta and Cu(i)-Abeta can reduce nitrite to nitric oxide (NO), an important biological messenger also related to AD, and thus behave as nitrite reductases. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 6 | However these complexes reduce nitrite at different rates with heme(III)-Cu(i)-Abeta being the fastest following an inner sphere electron transfer mechanism. | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 7 | The rest of the metal-Abeta adducts follow an outer sphere electron transfer mechanism during nitrite reduction. | Nitrites | amyloid beta precursor protein | Homo sapiens |