Title : UPLC-HRMS and NMR applied in the evaluation of solid-phase extraction methods as a rational strategy of dereplication of Phyllanthus spp. aiming at the discovery of cytotoxic metabolites.

Pub. Date : 2019 Jul 1

PMID : 31071579






1 Functional Relationships(s)
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1 The SPE (MeOH:H2O 70:30 with C18 cartridges) samples showed greater in vitro cytotoxicity than the crude extracts, with IC50 ranging from 8.01 to 94.92 mug mL-1 against the tumor lines tested. Methanol L1 cell adhesion molecule Mus musculus