Title : mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.

Pub. Date : 2019 Jul 3

PMID : 31056400






2 Functional Relationships(s)
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1 administration of the hCitrin-mRNA resulted in a significant reduction in (1) hepatic citrulline and blood ammonia levels following oral sucrose challenge and (2) sucrose aversion, hallmarks of hCitrin deficiency. Sucrose solute carrier family 25 member 13 Homo sapiens
2 administration of the hCitrin-mRNA resulted in a significant reduction in (1) hepatic citrulline and blood ammonia levels following oral sucrose challenge and (2) sucrose aversion, hallmarks of hCitrin deficiency. Sucrose solute carrier family 25 member 13 Homo sapiens