Protein Name solute carrier family 25 member 13
Organism Homo sapiens
Gene ID 10165
Gene Symbol

SLC25A13

UniProt Q9UJS0 (CMC2_HUMAN)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 104
Description

solute carrier family 25 member 13

Gene Summary

This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

synonyms
  • electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial
  • ARALAR-related gene 2
  • calcium-binding mitochondrial carrier protein Aralar2
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Properties