Title : Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.

Pub. Date : 2019

PMID : 31049134






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Prevention of Huntington"s Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress. tolfenamic acid huntingtin Mus musculus
2 Tolfenamic acid decreased the expression of mutant huntingtin in the striatum of 20-week-old R6/1 mice by inhibiting specificity protein 1 expression and enhancing autophagic function. tolfenamic acid huntingtin Mus musculus