Title : Nitric oxide blockade in mediodorsal thalamus impaired nicotine/ethanol-induced memory retrieval in rats via inhibition of prefrontal cortical pCREB/CREB signaling pathway.

Pub. Date : 2019 Jul

PMID : 31047996






4 Functional Relationships(s)
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1 Nitric oxide blockade in mediodorsal thalamus impaired nicotine/ethanol-induced memory retrieval in rats via inhibition of prefrontal cortical pCREB/CREB signaling pathway. Nicotine cAMP responsive element binding protein 1 Rattus norvegicus
2 Ethanol-induced amnesia, however, decreased this ratio in the PFC while the co-administration of nicotine and ethanol increased the PFC CREB signaling. Nicotine cAMP responsive element binding protein 1 Rattus norvegicus
3 Interestingly, the inhibitory effect of L-NAME and the potentiating effect of l-arginine on nicotine response were associated with the decrease and increase of the PFC p-CREB/CREB ratio respectively. Nicotine cAMP responsive element binding protein 1 Rattus norvegicus
4 Interestingly, the inhibitory effect of L-NAME and the potentiating effect of l-arginine on nicotine response were associated with the decrease and increase of the PFC p-CREB/CREB ratio respectively. Nicotine cAMP responsive element binding protein 1 Rattus norvegicus