Title : Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy.

Pub. Date : 2019 Jul

PMID : 31039321






1 Functional Relationships(s)
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Protein Name
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1 Mitoxantrone, daunorubicin, and vinorelbine are substrates of one or more of the ABCG2, ABCB1, or ABCC1 efflux transporters expressed to varying extents in the selected cell lines. Daunorubicin ATP binding cassette subfamily C member 1 Homo sapiens