Title : Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells.

Pub. Date : 2019 Apr 27

PMID : 31035592






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Among the enzymes mediating this plasticity through bidirectional conversion of pyruvate and lactate, the lactate dehydrogenase A (LDHA) and lactate dehydrogenase B (LDHB), are indicated. Lactic Acid lactate dehydrogenase B Homo sapiens
2 Among the enzymes mediating this plasticity through bidirectional conversion of pyruvate and lactate, the lactate dehydrogenase A (LDHA) and lactate dehydrogenase B (LDHB), are indicated. Lactic Acid lactate dehydrogenase B Homo sapiens
3 LDHA has a higher affinity for pyruvate, preferentially converting pyruvate to lactate, and NADH to NAD+ in anaerobic conditions, whereas LDHB possess a higher affinity for lactate, preferentially converting lactate to pyruvate, and NAD+ to NADH, when oxygen is abundant. Lactic Acid lactate dehydrogenase B Homo sapiens
4 LDHA has a higher affinity for pyruvate, preferentially converting pyruvate to lactate, and NADH to NAD+ in anaerobic conditions, whereas LDHB possess a higher affinity for lactate, preferentially converting lactate to pyruvate, and NAD+ to NADH, when oxygen is abundant. Lactic Acid lactate dehydrogenase B Homo sapiens