Title : Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis.

Pub. Date : 2019 Jul 5

PMID : 31028741






1 Functional Relationships(s)
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1 These effects were associated with an upregulation of uncoupling protein 2 (UCP2) and the activation of its upstream Sirtuin 1 (SIRT1)/(Liver kinase B1) LKB1- (Adenosine monophosphate-activated protein kinase) AMPK axis. Adenosine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens