Title : Pseudolaric acid B exhibits anti-cancer activity on human hepatocellular carcinoma through inhibition of multiple carcinogenic signaling pathways.

Pub. Date : 2019 Jun

PMID : 31004883






2 Functional Relationships(s)
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1 Moreover, abnormal GSK-3beta/beta-catenin signaling in HepG2 cells was remarkably suppressed by PAB treatment. pseudolaric acid B glycogen synthase kinase 3 beta Homo sapiens
2 CONCLUSION: Taken together, our results suggest that PAB exerts anti-cancer activity in HCC cells through inhibition of STAT3, ERK1/2, Akt, and GSK-3beta/beta-catenin carcinogenic signaling pathways, and may be used as a phytomedicine in the treatment of HCC. pseudolaric acid B glycogen synthase kinase 3 beta Homo sapiens