Title : Apigenin Alleviates Myocardial Reperfusion Injury in Rats by Downregulating miR-15b.

Pub. Date : 2019 Apr 15

PMID : 30983593






1 Functional Relationships(s)
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1 RESULTS We found that the increased miR-15b expression during myocardial I-R injury in rats downregulated the expression of JAK2 and activity of the JAK2-STAT3 pathway, promoted myocardial apoptosis and ROS production, and aggravated myocardial I-R injury. Reactive Oxygen Species Janus kinase 2 Rattus norvegicus