Title : Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor α7 Subunit (α7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis.

Pub. Date : 2019

PMID : 30967878






2 Functional Relationships(s)
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1 Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor alpha7 Subunit (alpha7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis. Acetylcholine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Here, we show for the first time, that short-term HFD consumption impairs early nicotinic acetylcholine receptor alpha7 subunit (alpha7nAChR)- mediated signaling, one of the major components of the cholinergic anti-inflammatory pathway, with a focus on hypothalamic inflammation and innate immune response. Acetylcholine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus