Title : Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-κB inactivation.

Pub. Date : 2019 May 15

PMID : 30946805






2 Functional Relationships(s)
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1 Our in vitro study identified that pretreatment of dauricine dose-dependently inhibited pro-inflammatory cytokines including nitric oxide (NO), interleukin-1beta (IL1beta), IL6, tumor necrosis factor-alpha (TNFalpha), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX2) in LPS-stimulated macrophages. dauricine prostaglandin-endoperoxide synthase 2 Mus musculus
2 Our in vitro study identified that pretreatment of dauricine dose-dependently inhibited pro-inflammatory cytokines including nitric oxide (NO), interleukin-1beta (IL1beta), IL6, tumor necrosis factor-alpha (TNFalpha), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX2) in LPS-stimulated macrophages. dauricine prostaglandin-endoperoxide synthase 2 Mus musculus