Title : Effective nebulization of interferon-γ using a novel vibrating mesh.

Pub. Date : 2019 Apr 3

PMID : 30943978






3 Functional Relationships(s)
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1 Extensive aerosol studies (aerosol output and droplet analysis, non-invasive and invasive aerosol therapy) were conducted in line with regulatory requirements and characterization of the stability and bioactivity of the IFN-gamma post-nebulization was confirmed using SDS-PAGE and stimulation of Human C-X-C motif chemokine 10 (CXCL 10) also known as IFN-gamma-induced protein 10KDa (IP 10) expression from THP-1 derived macrophages (THP-1 cells). Sodium Dodecyl Sulfate interferon gamma Homo sapiens
2 SDS-PAGE gels indicated that IFN-gamma remains stable after nebulization by both devices and this was confirmed by bioactivity studies using a THP-1 cell model in which an alveolar macrophage response to IFN-gamma was determined. Sodium Dodecyl Sulfate interferon gamma Homo sapiens
3 SDS-PAGE gels indicated that IFN-gamma remains stable after nebulization by both devices and this was confirmed by bioactivity studies using a THP-1 cell model in which an alveolar macrophage response to IFN-gamma was determined. Sodium Dodecyl Sulfate interferon gamma Homo sapiens