Pub. Date : 2019 Jul 15
PMID : 30940655
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, RET and Src co-high expression was an independent unfavorable prognosis factor in melanoma patients with or without ICB through inhibiting the antitumor immune response. | indole-2-carboxylic acid | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 2 | CONCLUSIONS: Our data unveiled a new mechanism of alleviating IFNgamma-induced PD-L1 and IDO1 expression and provided a rationale to explore a novel combination of ICB with regorafenib clinically, especially in melanoma with RET/Src axis activation. | indole-2-carboxylic acid | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |