Title : SENP2 suppresses NF-κB activation and sensitizes breast cancer cells to doxorubicin.

Pub. Date : 2019 Jul 5

PMID : 30940449






2 Functional Relationships(s)
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1 Moreover, NF-kappaB pathway is activated in MCF-7/adr cells, however, treatment with Bay 11-7085, one specific inhibitor of this pathway, reverses resistance to doxorubicin, suggesting that NF-kappaB pathway activation contributes to doxorubicin resistance in MCF-7/adr cells. BAY 11-7085 nuclear factor kappa B subunit 1 Homo sapiens
2 Moreover, NF-kappaB pathway is activated in MCF-7/adr cells, however, treatment with Bay 11-7085, one specific inhibitor of this pathway, reverses resistance to doxorubicin, suggesting that NF-kappaB pathway activation contributes to doxorubicin resistance in MCF-7/adr cells. BAY 11-7085 nuclear factor kappa B subunit 1 Homo sapiens