Title : Platelet-binding of the von Willebrand factor.

Pub. Date : 1978 Jun 30

PMID : 309191






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The aggregation of platelets by the antibiotic, ristocetin, requires a plasma cofactor (VIII:vWF) and one or more specific binding sites on the platelet membrane. Ristocetin von Willebrand factor Homo sapiens
2 In the presence of ristocetin (1.5 mg/ml), from 70 to 90% of the 125I-VIII:vWF became platelet-bound. Ristocetin von Willebrand factor Homo sapiens
3 It is concluded that VIII:vWF binds to the platelet membrane in the presence of ristocetin. Ristocetin von Willebrand factor Homo sapiens