Pub. Date : 2019 Oct
PMID : 30913132
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Everolimus is a mammalian target of rapamycine (m-TOR) inhibitor that has been approved for the treatment of hormone receptor-positive advanced breast cancer, metastatic renal cancer and neuroendocrine tumors. | Everolimus | RAR related orphan receptor C | Homo sapiens |
| 2 | In this review, the authors will discuss the current evidences and perspectives, based on observational studies available, in favor of the TDM of everolimus in oncology focusing on (i) the management of everolimus in routine practice, (ii) the prerequisites for TDM of everolimus in oncology, (iii) the pharmacodynamics (including a description of the biomarker of resistance and mutations in m-TOR) and (iv) a general outlook. | Everolimus | RAR related orphan receptor C | Homo sapiens |