Protein Name RAR related orphan receptor C
Organism Homo sapiens
Gene ID 6097
Gene Symbol

RORC

UniProt P51449 (RORG_HUMAN), Q6I9R9 (Q6I9R9_HUMAN), F1D8P6 (F1D8P6_HUMAN)
Relationships Total Number of functionally related compound(s) : 199
Total Number of Articles : 230
Description

RAR related orphan receptor C

Gene Summary

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • nuclear receptor ROR-gamma
  • nuclear receptor RZR-gamma
  • nuclear receptor subfamily 1 group F member 3
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Properties