Title : Phasic change and apoptosis regulation of JAK2/STAT3 pathway in a type 2 diabetic rat model.

Pub. Date : 2019

PMID : 30899391






3 Functional Relationships(s)
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1 We examined the interactions of metformin and sitagliptin treatment with the JAK2/STAT3 pathway and cardiac remodeling. Sitagliptin Phosphate Janus kinase 2 Rattus norvegicus
2 The superior cardio-protective effect of metformin over sitagliptin treatment may partly account for the differences we observed in JAK2/STAT3 activation, indicating that measuring JAK2/STAT3 pathway coupled with metformin treatment may give insight into a more promising DM treatment. Sitagliptin Phosphate Janus kinase 2 Rattus norvegicus
3 The superior cardio-protective effect of metformin over sitagliptin treatment may partly account for the differences we observed in JAK2/STAT3 activation, indicating that measuring JAK2/STAT3 pathway coupled with metformin treatment may give insight into a more promising DM treatment. Sitagliptin Phosphate Janus kinase 2 Rattus norvegicus