Pub. Date : 2019
PMID : 30890941
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits. | Ibogaine | glial cell derived neurotrophic factor | Rattus norvegicus |
2 | Recent work has suggested that ibogaine effects on alcohol self-administration in rats are related to the release of Glial cell Derived Neurotrophic Factor (GDNF) in the Ventral Tegmental Area (VTA), a mesencephalic region which hosts the soma of dopaminergic neurons. | Ibogaine | glial cell derived neurotrophic factor | Rattus norvegicus |
3 | Recent work has suggested that ibogaine effects on alcohol self-administration in rats are related to the release of Glial cell Derived Neurotrophic Factor (GDNF) in the Ventral Tegmental Area (VTA), a mesencephalic region which hosts the soma of dopaminergic neurons. | Ibogaine | glial cell derived neurotrophic factor | Rattus norvegicus |
4 | Although previous reports have shown ibogaine"s ability to induce GDNF expression in rat midbrain, there are no studies addressing its effect on the expression of GDNF and other neurotrophic factors (NFs) such as Brain Derived Neurotrophic Factor (BDNF) or Nerve Growth Factor (NGF) in distinct brain regions containing dopaminergic neurons. | Ibogaine | glial cell derived neurotrophic factor | Rattus norvegicus |