Title : Autophagy induction by xanthoangelol exhibits anti-metastatic activities in hepatocellular carcinoma.

Pub. Date : 2019 Apr

PMID : 30883849






3 Functional Relationships(s)
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1 Mechanistically, XAG induced autophagy via activation of the AMPK/mTOR signaling pathway, and XAG treatment dramatically increased the expression of p-AMPK while decreasing p-mTOR expression. xanthoangelol mechanistic target of rapamycin kinase Homo sapiens
2 Mechanistically, XAG induced autophagy via activation of the AMPK/mTOR signaling pathway, and XAG treatment dramatically increased the expression of p-AMPK while decreasing p-mTOR expression. xanthoangelol mechanistic target of rapamycin kinase Homo sapiens
3 Taken together, our results revealed that autophagy via the activation of AMPK/mTOR pathway is essential for the anti-metastatic effect of XAG against HCC. xanthoangelol mechanistic target of rapamycin kinase Homo sapiens