Title : Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.

Pub. Date : 2019 Apr 5

PMID : 30862161






1 Functional Relationships(s)
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Protein Name
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1 Several of these pyridine-fused rigid polyheterocycles are shown to bind to Abeta and alpha-synuclein fibrils, which are associated with neurodegenerative diseases. pyridine amyloid beta precursor protein Homo sapiens